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poly l lactic acid  (Galderma Inc)

 
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    Galderma Inc poly l lactic acid
    Poly L Lactic Acid, supplied by Galderma Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/poly+l+lactic+acid/acid+l+lactic+poly/10__36849_slash_jdd__9928-1-0-3
    Average 86 stars, based on 1 article reviews
    poly l lactic acid - by Bioz Stars, 2026-10
    86/100 stars

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    Article Title: Safety and Effectiveness of Two Reconstitution Volumes of Poly-L-Lactic Acid for Correction of Décolletage Wrinkles
    Article Snippet: Background: Aesthetic patients are increasingly aware of the contrast between rejuvenated facial skin and untreated aging skin of the décolletage, and frequently request cosmetic enhancement of this area.. Poly-L-lactic acid (Sculptra®, Galderma; PLLA-SCA) is a regenerative biostimulator that stimulates collagen and elastin production to help regenerate the skin’s inner structure.. Objective: This 9-month, open-label study investigated the effectiveness and safety of correcting décolletage wrinkles with PLLA-SCA using 2 reconstitution volumes.

    Article Title: Aesthetic considerations for treating the North American multi-ethnic patient: Thriving in diversity international roundtable series.
    Article Snippet: Across different areas of medicine, clinical trial investigators, regulators, individual physicians, and patients are becoming increasingly aware of the importance of racial and ethnic diversity for understanding treatment outcomes.1,2 In aesthetics, where outcomes are techniquedependent and tied to the clinician's ability to tailor treatment to the needs of individual patients, the benefits of inclusivity and diversity in product development, clinical studies, and education cannot be understated.. The United States 2021 Census reports that the US population is 59.3% nonHispanic White, 18.9% Hispanic or Latino, 13.6% Black or African American, 6.1% Asian, and 2.9% two or more races.3 The United States is becoming increasingly diverse, and within younger generations the percentage and Received: 25 August 2022 | Accepted: 27 September 2022 DOI: 10.1111/jocd.15422

    Article Title: Poly-L-Lactic Acid in Facial Rejuvenation: Volumetric Data Supporting Regenerative Outcomes
    Article Snippet: Poly-L-lactic acid (Sculptra ® , PLLA-SCA ® , Galderma Laboratories, Lausanne, Switzerland) is an alpha-hydroxy acid that has been in clinical use for many years, since its introduction in Europe in 1999.

    Article Title: Treatment of Facial Lipoatrophy Secondary to Subcutaneous Panniculitis-Like T-Cell Lymphoma
    Article Snippet: the lesion past the vermilion lip to the vermilion border or scarring at the border, suggesting the chronicity of the process, as with Case 4.. In patients at risk of GVHD, as in Cases 1, 2, and 3, GVHD should be considered, keeping inmind that patients with GVHD are also at higher risk of carcinoma.. After surgical intervention for neoplastic lesions, field treatment for actinic cheilitis or borderline lesions may be considered with PDT (as in Case 3), topical 5-fluorouracil, CO2 laser, or other modalities.

    Article Title: Fibroblast Rejuvenation: A Key Component to Antiaging
    Article Snippet: T he global antiaging industry in 2025 has been estimated to be worth more than $20 billion and grew more than 10% every year for the past 20 years which represents the popularity and demand for enhancing one’s personal appearance.. This trend is not new as the human species has striven to enhance personal beauty for millennia with different forms of “make-up,” tattoos, wigs, and clothing.. 1 Beauty is defined differently by cultures, but facial symmetry is hard-wired into virtually all life-forms, even at birth, as it represents health and fertility.

    Isolation:

    Article Title: Are you up-to-date on dermal fillers?
    Article Snippet: .. To date, there are now 4 groups of approved fillers: (1) HA (Belotero Balance [Merz North America, Inc], Juvèderm products [Allergan], Restylane products [Galderma Laboratories, LP], Resilient HA products [Revance Therapeutics Inc and Teoxane SA]), (2) calcium hydroxylapatite (Radiesse [Merz North America, Inc]), (3) poly-L-lactic acid (Sculptra Aesthetic [Galderma Laboratories, LP]), and (4) polymethylmethacrylate (Bellafill [Suneva Medical, Inc]).1-3 Given the versatility of this wide portfolio of products, which often are used in combination with one another, we have advanced from the early goals of filling isolated lines or wrinkles on the face to the 3-dimensional restructuring of an entire treatment area. ..



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    Outline of the experimental setting: Hybridization of CaCO3/CaCO 3 &CaP and PLLA, scaffold production using SLS, implantation into minipigs for 4 weeks and 13 weeks.

    Journal: Polymers

    Article Title: Bone Regeneration in SLS-Manufactured Resorbable 3D-Scaffolds—An Experimental Pilot Study in Minipigs

    doi: 10.3390/polym17182498

    Figure Lengend Snippet: Outline of the experimental setting: Hybridization of CaCO3/CaCO 3 &CaP and PLLA, scaffold production using SLS, implantation into minipigs for 4 weeks and 13 weeks.

    Article Snippet: In brief, poly-L-lactic acid (PLLA) (Resomer L206 S, Evonik, Essen, Germany, inherent viscosity range 0.8–1.2 gL/g) granules and spherulite-shaped precipitated calcium carbonate—with and without CaP (calcium phosphate coating (4%)—were dry processed in an impact mill (NHS-1, Tokyo 143, Japan) at 6400 rpm, leading to an inclusion of the spherulites into the PLLA granules.

    Techniques: Hybridization

    ( A ): cylindrical scaffold of 7 mm diameter and 5 mm height; ( B ): scaffold with 800 µm scaffold web thickness, bar: 1 mm; ( C ): scaffold with 1000 µm scaffold web thickness, bar: 1 mm; ( D ): PLLA-CaCO 3 scaffold, bar: 200 µm; ( E ): PLLA-CaCO 3 /CaP scaffold, a large number of unmelted polymer composite granules is attached to the scaffold surface as residuals after laser sintering, bar: 200 µm.

    Journal: Polymers

    Article Title: Bone Regeneration in SLS-Manufactured Resorbable 3D-Scaffolds—An Experimental Pilot Study in Minipigs

    doi: 10.3390/polym17182498

    Figure Lengend Snippet: ( A ): cylindrical scaffold of 7 mm diameter and 5 mm height; ( B ): scaffold with 800 µm scaffold web thickness, bar: 1 mm; ( C ): scaffold with 1000 µm scaffold web thickness, bar: 1 mm; ( D ): PLLA-CaCO 3 scaffold, bar: 200 µm; ( E ): PLLA-CaCO 3 /CaP scaffold, a large number of unmelted polymer composite granules is attached to the scaffold surface as residuals after laser sintering, bar: 200 µm.

    Article Snippet: In brief, poly-L-lactic acid (PLLA) (Resomer L206 S, Evonik, Essen, Germany, inherent viscosity range 0.8–1.2 gL/g) granules and spherulite-shaped precipitated calcium carbonate—with and without CaP (calcium phosphate coating (4%)—were dry processed in an impact mill (NHS-1, Tokyo 143, Japan) at 6400 rpm, leading to an inclusion of the spherulites into the PLLA granules.

    Techniques: Polymer

    Representative cross-sections through the scaffolds, Alizarin–Methylene Blue stain (ar: 2000 µm): White arrows indicate bone ingrowth into the scaffolds from the defect walls. Upper row 4 weeks : ( A ): Group 1/PLLA-CaCO 3 scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ); ( B ): Group 2/PLLA-CaCO 3 scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ); ( C ): Group 3/PLLA-CaCO 3 /CaP scaffolds with 1000 µm scaffold web thickness, (pore volume 69 mm 3 ); ( D ): Group 4/PLLA-CaCO 3 /CaP scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ). Lower row: 13 weeks ( E ): Group 1/PLLA-CaCO 3 scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ); ( F ): Group 2/PLLA-CaCO 3 scaffolds with 800 µm scaffold web thickness (pore volume 78 mm 3 ); ( G ): Group 3/PLLA-CaCO 3 /CaP scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ). White arrows indicate bone ingrowth into the scaffolds with almost complete pore fill. ( H ): Group 4/PLLA-CaCO 3 /CaP scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ).

    Journal: Polymers

    Article Title: Bone Regeneration in SLS-Manufactured Resorbable 3D-Scaffolds—An Experimental Pilot Study in Minipigs

    doi: 10.3390/polym17182498

    Figure Lengend Snippet: Representative cross-sections through the scaffolds, Alizarin–Methylene Blue stain (ar: 2000 µm): White arrows indicate bone ingrowth into the scaffolds from the defect walls. Upper row 4 weeks : ( A ): Group 1/PLLA-CaCO 3 scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ); ( B ): Group 2/PLLA-CaCO 3 scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ); ( C ): Group 3/PLLA-CaCO 3 /CaP scaffolds with 1000 µm scaffold web thickness, (pore volume 69 mm 3 ); ( D ): Group 4/PLLA-CaCO 3 /CaP scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ). Lower row: 13 weeks ( E ): Group 1/PLLA-CaCO 3 scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ); ( F ): Group 2/PLLA-CaCO 3 scaffolds with 800 µm scaffold web thickness (pore volume 78 mm 3 ); ( G ): Group 3/PLLA-CaCO 3 /CaP scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ). White arrows indicate bone ingrowth into the scaffolds with almost complete pore fill. ( H ): Group 4/PLLA-CaCO 3 /CaP scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ).

    Article Snippet: In brief, poly-L-lactic acid (PLLA) (Resomer L206 S, Evonik, Essen, Germany, inherent viscosity range 0.8–1.2 gL/g) granules and spherulite-shaped precipitated calcium carbonate—with and without CaP (calcium phosphate coating (4%)—were dry processed in an impact mill (NHS-1, Tokyo 143, Japan) at 6400 rpm, leading to an inclusion of the spherulites into the PLLA granules.

    Techniques: Staining

    Representative cross-sections through the scaffolds, peroxidase stain of osteocalcin (Bar: 1000 µm): Intense positive reactions for osteocalcin throughout the tissue grown into the scaffold volume (black asterisks). Upper row 4 weeks : ( A ): Group 1/PLLA-CaCO 3 scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ); ( B ): Group 2/PLLA-CaCO 3 scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ); ( C ): Group 3/PLLA-CaCO 3 /CaP scaffolds with 1000 µm scaffold web thickness, (pore volume 69 mm 3 ); ( D ): Group 4/PLLA-CaCO 3 /CaP scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ). Lower Row: 13 weeks. Positive reaction for osteocalcin has decreased to small seams on the surface of the newly formed bone and the scaffold surface (black arrows). ( E ): Group 1/PLLA-CaCO 3 scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ); ( F ): Group 2/PLLA-CaCO 3 scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ); ( G ): Group 3/PLLA-CaCO 3 /CaP scaffolds with 1000 µm scaffold web thickness, (pore volume 69 mm 3 ); ( H ): Group 4/PLLA-CaCO 3 /CaP scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ).

    Journal: Polymers

    Article Title: Bone Regeneration in SLS-Manufactured Resorbable 3D-Scaffolds—An Experimental Pilot Study in Minipigs

    doi: 10.3390/polym17182498

    Figure Lengend Snippet: Representative cross-sections through the scaffolds, peroxidase stain of osteocalcin (Bar: 1000 µm): Intense positive reactions for osteocalcin throughout the tissue grown into the scaffold volume (black asterisks). Upper row 4 weeks : ( A ): Group 1/PLLA-CaCO 3 scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ); ( B ): Group 2/PLLA-CaCO 3 scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ); ( C ): Group 3/PLLA-CaCO 3 /CaP scaffolds with 1000 µm scaffold web thickness, (pore volume 69 mm 3 ); ( D ): Group 4/PLLA-CaCO 3 /CaP scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ). Lower Row: 13 weeks. Positive reaction for osteocalcin has decreased to small seams on the surface of the newly formed bone and the scaffold surface (black arrows). ( E ): Group 1/PLLA-CaCO 3 scaffolds with 1000 µm scaffold web thickness (pore volume 69 mm 3 ); ( F ): Group 2/PLLA-CaCO 3 scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ); ( G ): Group 3/PLLA-CaCO 3 /CaP scaffolds with 1000 µm scaffold web thickness, (pore volume 69 mm 3 ); ( H ): Group 4/PLLA-CaCO 3 /CaP scaffolds with 800 µm scaffold web thickness, (pore volume 78 mm 3 ).

    Article Snippet: In brief, poly-L-lactic acid (PLLA) (Resomer L206 S, Evonik, Essen, Germany, inherent viscosity range 0.8–1.2 gL/g) granules and spherulite-shaped precipitated calcium carbonate—with and without CaP (calcium phosphate coating (4%)—were dry processed in an impact mill (NHS-1, Tokyo 143, Japan) at 6400 rpm, leading to an inclusion of the spherulites into the PLLA granules.

    Techniques: Staining